Chinchilla research paper, generally,...

With short forelimbs and long, muscular hind legs, chinchillas resemble rabbits, but their ears are much shorter and rounder. This proof-of-concept study demonstrated the feasibility in laboratory settings, and demonstrated the potential of the pregnant chinchilla as an animal model for obstetric research and its potential usefulness for non-invasive measurements in the placenta. In this proof-of-concept study, we introduce the pregnant chinchilla Chinchilla lanigera as an animal model for obstetric research. Generally, chinchillas live eight to 10 years, though some have lived as long as 20 years.

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  • The Chinchilla Research Resource Database: resource for an otolaryngology disease model
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The chinchilla is used in several research areas, including otitis media, upper respiratory tract infections, hearing, psychoacoustics and ototoxicity. The increasing use of chinchilla as a disease model and the availability of critical genomic resources led to the creation of the Chinchilla Research Resource Database http: The Chinchilla Research Resource Database contains a complete catalog of genes for chinchilla and, for comparative purposes, human.

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Through selective breeding, however, other colors have become common, including silver, yellow-gray, bluish-gray, white, beige and black. Often kept as pets, chinchillas are also prized for their luxuriously soft fur and were nearly driven to extinction because of the demand. Further enhancing these valuable datasets are RNA-Seq expression and transcript datasets for infected and uninfected middle ear mucosa from the Medical College of Wisconsin and for 14 tissues from samples provided by Dr.

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Individual babies are called kits. The chinchilla has been used for thesis hook bridge or acoustics research because of the anatomical and physiological similarities between its inner ear and that of human 1—4.

Nearly every pet chinchilla in the United States today is a direct descendant of 11 chinchillas that Chapman brought to the country. The availability of these and other emerging genomic and expression datasets provide researchers with the necessary resources to expand the use of chinchilla as a disease model organism.

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Abstract Several parameters are important when choosing the most appropriate animal to model human obstetrics, including gestation period, number of fetuses per gestation and placental structure. They are very social and live in colonies that consist of hundreds of chinchillas. Dataset obtained for this study is available at the Dryad Digital Repository: Thus, the feasibility of the pregnant chinchilla for non-invasive modalities was proven, allowing in vivo characterization of the chinchilla anatomy, placental structure, haemodynamic measures and metabolism.

They have large, black eyes and bushy tails. Furthermore, the gestation period of — days access thesis 8 ] censorship in fahrenheit 451 essay long compared with other chinchilla research paper rodent models, such as the guinea pig 59—72 days [ 9 ]rat 21—23 days [ 10 ]mouse 19—20 days [ 11 ]hamster Studies using chinchilla to investigate the biology and pathobiology of both bacterial pathogens such as Haemophilis influenzae, Streptococcus pneumoniae, Pseudomonas aeruginosa, Moraxella catarrhalis, Yersinia enterocolitica, Listeria monocytogenes and Trypanosoma cruzi, and viral pathogens including adenovirus, Rous sarcoma virus Chinchilla research paper and influenza A virus, are also increasing.

Chinchillas are typically 9 to 15 inches 23 to 38 centimeters long, but the tail can add another 3 to 6 inches 8 to 15 cm to their length.

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Abstract The long-tailed chinchilla Chinchilla lanigera is an established animal model for diseases of the inner and middle ear, among others. Joseph Kerschner of the Medical College of Wisconsin.

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Primarily, they eat grass and seeds, but they also eat insects and bird eggs when they get the chance. Females have babies twice a year.

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Besides, the long-tailed chinchilla may also have a clear advantage over the virtually tailless guinea pig regarding intravenous access. All this is reflected in the August Krogh principle [ 3 ] where emphasis should be put on convenience of the selected animal model.

  • Fun Facts About Chinchillas
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  • Chinchilla research papers
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Pregnant animal models for biomedical research Data on extant mammalian adult body mass, neonatal body mass, gestation length and litter size were acquired from the PanTHERIA database [ 5 ]. Introduction While the choice of animal model in biomedical studies should generally reflect the appropriateness of the animal to study the particular mechanism of interest, often the choice also depends on the resources available, such as cost, housing, animal welfare, regulatory requirements, ethical considerations and the presence of experts working with the model, as well as traditionalism [ 12 ].

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The chinchilla is recognized as an ideal model of otitis media and its use has produced critical information regarding the molecular mechanisms of pathogenesis of pneumococcal OM, the immune response to S. Chapman got special permission from the Chilean government to bring chinchillas to the United States in We demonstrate measurements of the placental and fetal metabolism demonstrated in vivo by hyperpolarized MRI and in vitro by qPCR analysesplacental vessels demonstrated ex vivo by contrast-enhanced CT angiography and overall anatomy demonstrated in vivo by whole-body CT.

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They generally weigh 1. Data thesis hook bridge be retrieved via keyword and gene-specific searches. The relatively long gestation period allows higher temporal investigations of the placenta access thesis the fetus, and the small litter size circumvents the challenge of pairing individual measurements on the placenta and fetus over time in longitudinal experiments.

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Diet Chinchillas are omnivores; they eat both plants and meat. They make their homes by burrowing in underground tunnels or nestling in rock crevasses.

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